In the present study, we focus on low latitude middle atmospheric dynamics over Thumba (8.50 N, 770 E), a low-latitude rocket launching station in India. Several campaigns were carried out at this site to investigate the middle atmospheric dynamical phenomena using balloon, rockets and radar observations. Many of the investigations focused on vertical coupling of the lower and middle atmosphere through spectrum of propagating waves. Climatology and long-term trends of winds and temperature using 45 years of radiosonde observations in the troposphere, 26 years of rocket observations in the stratosphere and lower mesosphere and 11 years of meteor radar observations in the mesosphere and lower thermosphere is discussed. The long period oscillations and their variability in the middle atmospheric winds viz., quasi biennial oscillation (QBO), stratospheric semi-annual oscillations (SSAO) and mesospheric semi-annual oscillations (MSAO) are discussed. The general features and propagation characteristics of tides, gravity and planetary waves (including equatorial waves) are investigated including their role in driving the QBO, SSAO and MSAO through wave-mean flow interactions. A detailed depiction on how these waves couples the different layers of the atmosphere and how they interact among themselves through wave-wave interactions is also presented. The significance of the present study lies in synthesizing the middle atmospheric research carried out for last four decades at Thumba using host of experiments and campaigns and its contributions towards understanding the middle atmospheric processes.